Product Name:

NebuSelect™ Recombinant Human DSG-2/Desmoglein-2, His-tag

Catalog#:

NBL-242733

Description:

NebuSelect™ Recombinant Human DSG-2/Desmoglein-2, His-tag(Cat#NBL-242733) is expressed in HEK293 with His tag at the C-Terminus.It contains Ala50-Gly609.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 63.6 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Bis-Tris PAGE result.

Target Name:

DSG-2/Desmoglein-2; Desmoglein-2; HDGC; DSG2; CDHF5; ARVC10; CMD1BB; MGC117036; MGC117037

Target Information:

Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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