Product Name:

NebuSelect™ Recombinant Human DR6/TNFRSF21, His-tag

Catalog#:

NBL-242735

Description:

NebuSelect™ Recombinant Human DR6/TNFRSF21, His-tag(Cat#NBL-242735) is expressed in HEK293 with His tag at the C-Terminus.It contains Gln42-His349.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 34.3 kDa. Due to glycosylation, the protein migrates to 65-80 kDa based on Bis-Tris PAGE result.

Target Name:

DR6/TNFRSF21; Death receptor 6; CD358; TNFRSF21; DR6; BM-018; MGC31965

Target Information:

beta-amyloid precursor protein (APP) and death receptor 6 (DR6, also known as TNFRSF21) activate a widespread caspase-dependent self-destruction program. DR6 is broadly expressed by developing neurons, and is required for normal cell body death and axonal pruning both in vivo and after trophic-factor deprivation in vitro.DR6 is activated locally by an inactive surface ligand(s) that is released in an active form after trophic-factor deprivation.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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