Product Name:

NebuSelect™ Recombinant Human CRTAM, His-tag

Catalog#:

NBL-242770

Description:

NebuSelect™ Recombinant Human CRTAM, His-tag(Cat#NBL-242770) is expressed in HEK293 with His tag at the C-Terminus.It contains Ser18-Gly287.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 31.1 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.

Target Name:

CRTAM; CD355 antigen; CD355; CRTAM

Target Information:

Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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