Product Name:

NebuSelect™ Recombinant Human Factor H/CFH, His-tag

Catalog#:

NBL-242814

Description:

NebuSelect™ Recombinant Human Factor H/CFH, His-tag(Cat#NBL-242814) is expressed in HEK293 with His tag at the C-Terminus.It contains Ser860-Arg1231.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 42.8 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Bis-Tris PAGE result.

Target Name:

Factor H/CFH; Complement factor H; H factor 1; CFH; HF; HF1; HF2; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HUS

Target Information:

Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations and polymorphisms that affect recognition of self by factor H are associated with diseases of complement dysregulation, such as age-related macular degeneration and atypical haemolytic uremic syndrome. In addition, pathogens (i.e., non-self) and cancer cells (i.e., altered-self) can hijack factor H to evade the immune response.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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