Product Name:

NebuSelect™ Recombinant Human CD40 Ligand/TNFSF5 Trimer, monoFc-tag

Catalog#:

NBL-242827

Description:

NebuSelect™ Recombinant Human CD40 Ligand/TNFSF5 Trimer, monoFc-tag(Cat#NBL-242827) is expressed in HEK293 with monomeric hFc tag at the N-Terminus.It contains Met113-Leu261.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 74.9 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Bis-Tris PAGE result.

Target Name:

CD40 Ligand/TNFSF5 Trimer; CD40L; CD40LG; CD154; TNFSF5; TNFSF5IMD3; CD40LIGM; gp39; HIGM1; T-BAM; TRAP; IGM; IMD3; CD40 Ligand

Target Information:

CD40 ligand or CD40L, also called CD154,- is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.-.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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