Product Name:

NebuSelect™ Recombinant Mouse APCDD1, His-tag

Catalog#:

NBL-243099

Description:

NebuSelect™ Recombinant Mouse APCDD1, His-tag(Cat#NBL-243099) is expressed in HEK293 with His tag at the C-Terminus.It contains Leu27-Thr492.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 54.4 kDa. Due to glycosylation, the protein migrates to 65-68 kDa based on Bis-Tris PAGE result.

Target Name:

APCDD1; Apcdd1; Drapc1; B7323; FP7019; HHS; HTS; HYPT1

Target Information:

Adenomatosis polyposis coli downregulated 1 (APCDD1), a negative regulator of Wnt signaling, was examined to understand detailed mechanisms underlying Wnt signaling tooth development. In situ hybridization showed that Apcdd1 was expressed in the condensed mesenchyme at the bud stage, and in the inner enamel epithelium (IEE), including enamel knot (EK) at the cap stage. APCDD1 modulates the gene expression of Wnt- and EK-related signaling molecules at the cap stage of tooth development, and is involved in tooth cusp patterning by modulating the epithelial rearrangement in the IEE.

Amino Acid Sequence: 

Leu27-Thr492

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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