Product Name:

NebuSelect™ Recombinant Human AMCase/CHIA, His-tag

Catalog#:

NBL-243114

Description:

NebuSelect™ Recombinant Human AMCase/CHIA, His-tag(Cat#NBL-243114) is expressed in HEK293 with His tag at the C-Terminus.It contains Tyr22-Ala476.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 51.2 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Bis-Tris PAGE result.

Target Name:

AMCase/CHIA; Acidic mammalian chitinase; AMCase; CHIA; CHIT2; EC 3.2.1.14; Chia1; YNL

Target Information:

Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans. The chitinase activity of AMCase was found to be causative in allergic inflammation and its expression was found to be induced by interleukin-13. CHIT1-1 is expressed by phagocytic cells and extremely high levels are seen in lysosomal storage diseases. Despite that AMCase expression in the inflammation is under investigation, little is known regarding its regulation during macrophages' full maturation and polarization.

Amino Acid Sequence: 

Tyr22-Ala476

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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