Product Name:

NebuSelect™ Recombinant Cynomolgus NPR1/NPRA, mFc-tag

Catalog#:

NBL-241138

Description:

NebuSelect™ Recombinant Cynomolgus NPR1/NPRA, mFc-tag(Cat#NBL-241138) is expressed in HEK293 with mFc (IgG1) tag at the C-terminus.It contains Gly33-Glu473.

Species:

Cynomolgus

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 74.56 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.

Target Name:

NPR1/NPRA

Target Information:

NPR1 (natriuretic peptide receptor 1), a receptor of ANP (atrial natriuretic peptide) whitch acting through NPR1, provokes hypotension. NPR1 was abundantly expressed in endothelial cells and smooth muscle cells of small arteries and arterioles. NPR1 plays a crucial role in ANP-mediated blood pressure regulation, presumably by a mechanism that is RGS2-dependent in the acute phase and RGS2-independent in the chronic phase.

Amino Acid Sequence: 

Gly33-Glu473

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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