Product Name:

NebuSelect™ Recombinant Rat FcRn, His-tag

Catalog#:

NBL-241140

Description:

NebuSelect™ Recombinant Rat FcRn, His-tag(Cat#NBL-241140) is expressed in HEK293 with His tag at the C-terminus.It contains Ala23-Ser298 (FCGRT) and Ile21-Met119 (B2M).

Species:

Rat

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 32.60 kDa (FCGRT) and 11.63 kDa (B2M). Due to glycosylation, the protein migrates to 45-60 kDa (FCGRT) and 13-15 kDa (B2M) based on Bis-Tris PAGE result.

Target Name:

FcRn

Target Information:

The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer.

Amino Acid Sequence: 

Ala23-Ser298(FCGRT) & Ile21-Met119(B2M)

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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