NBL-243155 NebuSelect™ Recombinant human PDGF-AA.pdf

Product Name:

NebuSelect™ Recombinant human PDGF-AA

Catalog#:

NBL-243155

Description:

NebuSelect™ Recombinant human PDGF-AA, His-tag(Cat#NBL-243155) is expressed in E.coli.

Species:

Human

Expression System:

E.coli

Molecular Weight: 

The protein has a predicted MW of 14.1kDa. 

Target Name:

PDGF-AA

Target Information:

Tumor necrosis factor ligand superfamily member 13 (TNFSF13) also known as a proliferation-inducing ligand (APRIL) is a member PDGF (Platelet-derived growth factor) is one among numerous growth factors that regulate cell growth and division. The PDGF family forms five dimeric ligands, PDGF-AA, PDGF-BB, PDGF-CC, PDGF-DD, and PDGF-AB, which activate cognate receptor tyrosine kinases PDGFR-α and PDGFR-β. Upon binding to its tyrosine kinase receptor PDGF-αα, PDGF-AA stimulates the proliferation of osteoblastic cells and may exert autocrine and paracrine effects in regulating bone-forming processes. PDGF-AA is the most well characterized mitogen that is not restricted to any kind of tumor cell type but was seen in osteoblastic cells as well as in pleomorphic tumor elements.

Accession:

P04085

Purity:

＞90%

Formulation:

Powder

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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